Ohio River Scenic Route crosses southern Ohio for 452 miles. It primarily follows US 50, US 52, and OH 7 from the Indiana state line to the Pennsylvania state line. The roads are primarily two-lane paved roads suitable for all vehicles. In eastern Ohio, OH 7 is a four-lane divided highway. Ohio River Scenic Route is generally open year-round.
Ohio River Scenic Route cuts across southern Ohio through hardwood forests and rocky hillsides. It travels through numerous historical towns and sites. In Steubenville is the restored Fort Steuben, a 1780s fort built under the command of Captain John Francis Hamtramck to protect the early land surveyors. The birthplace of Ulysses S. Grant is along the byway in Point Pleasant near Neville. The site contains a restored three-room cottage where the 18th President of the United States was born.
In addition to history lessons, Ohio River Scenic Route offers opportunities for outdoor recreation. A portion of the byway crosses Wayne National Forest where visitors will find trails, picnic areas, and camping opportunities. Vesuvius Recreation Area is north of Ironton and has two campgrounds situated on 200-acre Lake Vesuvius. The two campgrounds, Iron Ridge and Oak Hill, have a total of nearly 70 RV and tent campsites. They are generally open April through October.
Camping is also available in three state parks near the byway: Shawnee, Forked Run, and Beaver Creek. Shawnee State Park is open all year and has a total of 107 campsites with electric hookups. It also has a 50-room lodge and 25 family cottages. Forked Run State Park is on OH 124 and has nearly 200 campsites but none with hookups. The 917-acre park remains open all year. Near the byway’s eastern terminus is Beaver Creek State Park. It is 11 miles north of East Liverpool and has 55 RV and tent sites but none with hookups. It remains open year-round but facilities may be limited in winter.